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Sample size calculation in randomised phase II selection trials using a margin of practical equivalence

BACKGROUND: In rare cancers or subtypes of common cancers, a comparison of multiple promising treatments may be required. The selected treatment can then be assessed against the standard of care (if it exists) or used as a backbone for combinations with new, possibly targeted, agents. There could be...

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Detalles Bibliográficos
Autores principales: Dehbi, Hakim-Moulay, Hackshaw, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106856/
https://www.ncbi.nlm.nih.gov/pubmed/32228674
http://dx.doi.org/10.1186/s13063-020-04248-8