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Sample size calculation in randomised phase II selection trials using a margin of practical equivalence
BACKGROUND: In rare cancers or subtypes of common cancers, a comparison of multiple promising treatments may be required. The selected treatment can then be assessed against the standard of care (if it exists) or used as a backbone for combinations with new, possibly targeted, agents. There could be...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106856/ https://www.ncbi.nlm.nih.gov/pubmed/32228674 http://dx.doi.org/10.1186/s13063-020-04248-8 |