Synthesis and biological evaluation of 2-(4-methylsulfonyl phenyl) indole derivatives: multi-target compounds with dual antimicrobial and anti-inflammatory activities

Three series of 2-(4-methylsulfonylphenyl) indole derivatives have been designed and synthesized. The synthesized compounds were assessed for their antimicrobial, COX inhibitory and anti-inflammatory activities. Compound 7g was identified to be the most potent antibacterial candidate against strains...

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Detalles Bibliográficos
Autores principales: Shaker, Ahmed M. M., Abdelall, Eman K. A., Abdellatif, Khaled R. A., Abdel-Rahman, Hamdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106896/
https://www.ncbi.nlm.nih.gov/pubmed/32259135
http://dx.doi.org/10.1186/s13065-020-00675-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106896/
https://www.ncbi.nlm.nih.gov/pubmed/32259135
http://dx.doi.org/10.1186/s13065-020-00675-5

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