Cargando…
Synthesis and biological evaluation of 2-(4-methylsulfonyl phenyl) indole derivatives: multi-target compounds with dual antimicrobial and anti-inflammatory activities
Three series of 2-(4-methylsulfonylphenyl) indole derivatives have been designed and synthesized. The synthesized compounds were assessed for their antimicrobial, COX inhibitory and anti-inflammatory activities. Compound 7g was identified to be the most potent antibacterial candidate against strains...
Autores principales: | Shaker, Ahmed M. M., Abdelall, Eman K. A., Abdellatif, Khaled R. A., Abdel-Rahman, Hamdy M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106896/ https://www.ncbi.nlm.nih.gov/pubmed/32259135 http://dx.doi.org/10.1186/s13065-020-00675-5 |
Ejemplares similares
-
Design, synthesis, biological assessment and in silico ADME prediction of new 2-(4-(methylsulfonyl) phenyl) benzimidazoles as selective cyclooxygenase-2 inhibitors
por: Badawy, Mohamed A. S., et al.
Publicado: (2021) -
[4-(Methylsulfonyl)phenyl]acetic acid
por: Yuan, Yan-Qin, et al.
Publicado: (2008) -
2-[4-(Methylsulfonyl)phenyl]acetonitrile
por: Fun, Hoong-Kun, et al.
Publicado: (2011) -
Methyl c-1-cyano-t-2-methylsulfonyl-3-phenylcyclopropanecarboxylate
por: Vasin, Victor A., et al.
Publicado: (2011) -
Novel N-methylsulfonyl-indole derivatives: biological activity and COX-2/5-LOX inhibitory effect with improved gastro protective profile and reduced cardio vascular risks
por: Philoppes, John N., et al.
Publicado: (2022)