The mitochondria‐targeted anti‐oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance

OBJECTIVE: Mitochondrial dysfunction, oxidative stress and nucleus pulposus (NP) cell apoptosis are important contributors to the development and pathogenesis of intervertebral disc degeneration (IDD). Here, we comprehensively evaluated the effects of mitochondrial dynamics, mitophagic flux and Nrf2...

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Detalles Bibliográficos
Autores principales: Kang, Liang, Liu, Shiwei, Li, Jingchao, Tian, Yueyang, Xue, Yuan, Liu, Xiaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106957/
https://www.ncbi.nlm.nih.gov/pubmed/32020711
http://dx.doi.org/10.1111/cpr.12779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106957/
https://www.ncbi.nlm.nih.gov/pubmed/32020711
http://dx.doi.org/10.1111/cpr.12779

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