HJC0152 suppresses human non–small‐cell lung cancer by inhibiting STAT3 and modulating metabolism

OBJECTIVES: Signal transducer and activator of transcription 3 (STAT3) is constitutively activated and overexpressed in many cancers, including non–small‐cell lung cancer (NSCLC). We recently developed HJC0152 as an orally active STAT3 inhibitor. This study focused on investigating HJC0152's ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Lu, Li, Hang, Wu, Xin, Rao, Jun, Zhou, Jia, Fan, Saijun, Shen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106968/
https://www.ncbi.nlm.nih.gov/pubmed/32022328
http://dx.doi.org/10.1111/cpr.12777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106968/
https://www.ncbi.nlm.nih.gov/pubmed/32022328
http://dx.doi.org/10.1111/cpr.12777

Ejemplares similares