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PLCε knockdown enhances the radiosensitivity of castration-resistant prostate cancer via the AR/PARP1/DNA-PKcs axis

Radiotherapy (RT) has been used as a therapeutic option for treatment of prostate cancer (PCa) for a number of years; however, patients frequently develop RT resistance, particularly in castration-resistant PCa (CRPC), although the underlying mechanisms remain unknown. Understanding the underlying m...

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Detalles Bibliográficos
Autores principales: Pu, Jun, Li, Ting, Liu, Nanjing, Luo, Chunli, Quan, Zhen, Li, Luo, Wu, Xiaohou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108056/
https://www.ncbi.nlm.nih.gov/pubmed/32323799
http://dx.doi.org/10.3892/or.2020.7520