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In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

BACKGROUND: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection. Hydroxychloroquine shares the same mechanism of action as chloroquine, but its mor...

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Detalles Bibliográficos
Autores principales: Yao, Xueting, Ye, Fei, Zhang, Miao, Cui, Cheng, Huang, Baoying, Niu, Peihua, Liu, Xu, Zhao, Li, Dong, Erdan, Song, Chunli, Zhan, Siyan, Lu, Roujian, Li, Haiyan, Tan, Wenjie, Liu, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108130/
https://www.ncbi.nlm.nih.gov/pubmed/32150618
http://dx.doi.org/10.1093/cid/ciaa237