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MITA/STING: A central and multifaceted mediator in innate immune response

The recognition of nucleic acids is a general strategy used by the host to detect invading pathogens. Many studies have established that MITA/STING is a central component in the innate immune response to cytosolic DNA and RNA derived from pathogens. MITA can act both as a direct sensor of cyclic din...

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Detalles Bibliográficos
Autores principales: Ran, Yong, Shu, Hong-Bing, Wang, Yan-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108248/
https://www.ncbi.nlm.nih.gov/pubmed/24929887
http://dx.doi.org/10.1016/j.cytogfr.2014.05.003