Cargando…
MITA/STING: A central and multifaceted mediator in innate immune response
The recognition of nucleic acids is a general strategy used by the host to detect invading pathogens. Many studies have established that MITA/STING is a central component in the innate immune response to cytosolic DNA and RNA derived from pathogens. MITA can act both as a direct sensor of cyclic din...
Autores principales: | Ran, Yong, Shu, Hong-Bing, Wang, Yan-Yi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108248/ https://www.ncbi.nlm.nih.gov/pubmed/24929887 http://dx.doi.org/10.1016/j.cytogfr.2014.05.003 |
Ejemplares similares
-
Mitotic inactivation of the cGAS‒MITA/STING pathways
por: Zhong, Li, et al.
Publicado: (2021) -
The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response
por: Li, Chen, et al.
Publicado: (2021) -
SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA
por: Wei, Jin, et al.
Publicado: (2018) -
USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA
por: Zhang, Hong-Yan, et al.
Publicado: (2020) -
Human cytomegalovirus protein UL42 antagonizes cGAS/MITA-mediated innate antiviral response
por: Fu, Yu-Zhi, et al.
Publicado: (2019)