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Aptamer-based and aptazyme-based riboswitches in mammalian cells
Molecular recognition by RNA aptamers has been exploited to control gene expression in response to small molecules in mammalian cells. These mammalian synthetic riboswitches offer attractive features such as small genetic size and lower risk of immunological complications compared to protein-based t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Author. Published by Elsevier Ltd.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108311/ https://www.ncbi.nlm.nih.gov/pubmed/31238268 http://dx.doi.org/10.1016/j.cbpa.2019.05.018 |