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An evolving arsenal: viral RNA detection by RIG-I-like receptors

RIG-I-like receptors (RLRs) utilize a specialized, multi-domain architecture to detect and respond to invasion by a diverse set of viruses. Structural similarities among these receptors provide a general mechanism for double strand RNA recognition and signal transduction. However, each RLR has devel...

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Detalles Bibliográficos
Autores principales: Fitzgerald, Megan E, Rawling, David C, Vela, Adriana, Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108371/
https://www.ncbi.nlm.nih.gov/pubmed/24912143
http://dx.doi.org/10.1016/j.mib.2014.05.004