Cargando…
Large-scale integrated super-computing platform for next generation virtual drug discovery
Traditional drug discovery starts by experimentally screening chemical libraries to find hit compounds that bind to protein targets, modulating their activity. Subsequent rounds of iterative chemical derivitization and rescreening are conducted to enhance the potency, selectivity, and pharmacologica...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108376/ https://www.ncbi.nlm.nih.gov/pubmed/21723773 http://dx.doi.org/10.1016/j.cbpa.2011.06.005 |