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Bioproduction of ribavirin by green microbial biotransformation

Ribavirin is an antiviral compound widely used in Hepatitis C Virus therapy. Biotransformation of this nucleoside analogue using Escherichia coli ATCC 12407 as biocatalyst is herein reported. Reaction parameters such as microorganism amounts, substrate ratio and temperature were optimized reaching c...

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Detalles Bibliográficos
Autores principales: Rivero, Cintia W., De Benedetti, Eliana C., Lozano, Mario E., Trelles, Jorge A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108421/
https://www.ncbi.nlm.nih.gov/pubmed/32288593
http://dx.doi.org/10.1016/j.procbio.2015.03.015