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Viral targets of acylguanidines

Acylguanidines are a new class of antiviral compounds with the unique ability to target both RNA polymerase and transmembrane proteins of viruses from different families. Importantly, they inhibit proteins which are not targeted by existing antiviral therapies, for example, Vpu of HIV type 1, p7 of...

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Detalles Bibliográficos
Autores principales: Gazina, Elena V., Petrou, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108427/
https://www.ncbi.nlm.nih.gov/pubmed/22580299
http://dx.doi.org/10.1016/j.drudis.2012.05.002