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The influence of rare variants in circulating metabolic biomarkers

Circulating metabolite levels are biomarkers for cardiovascular disease (CVD). Here we studied, association of rare variants and 226 serum lipoproteins, lipids and amino acids in 7,142 (discovery plus follow-up) healthy participants. We leveraged the information from multiple metabolite measurements...

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Detalles Bibliográficos
Autores principales: Riveros-Mckay, Fernando, Oliver-Williams, Clare, Karthikeyan, Savita, Walter, Klaudia, Kundu, Kousik, Ouwehand, Willem H., Roberts, David, Di Angelantonio, Emanuele, Soranzo, Nicole, Danesh, John, Wheeler, Eleanor, Zeggini, Eleftheria, Butterworth, Adam S., Barroso, Inês
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108731/
https://www.ncbi.nlm.nih.gov/pubmed/32150548
http://dx.doi.org/10.1371/journal.pgen.1008605