Exploring the molecular structures that confer ligand selectivity for galanin type II and III receptors

Galanin receptors (GALRs) belong to the superfamily of G-protein coupled receptors. The three GALR subtypes (GALR1, GALR2, and GALR3) are activated by their endogenous ligands: spexin (SPX) and galanin (GAL). The synthetic SPX-based GALR2-specific agonist, SG2A, plays a dual role in the regulation o...

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Detalles Bibliográficos
Autores principales: Lee, Yoo-Na, Reyes-Alcaraz, Arfaxad, Yun, Seongsik, Lee, Cheol Soon, Hwang, Jong-Ik, Seong, Jae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108740/
https://www.ncbi.nlm.nih.gov/pubmed/32231393
http://dx.doi.org/10.1371/journal.pone.0230872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108740/
https://www.ncbi.nlm.nih.gov/pubmed/32231393
http://dx.doi.org/10.1371/journal.pone.0230872

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