Direct interaction of metastasis-inducing S100P protein with tubulin causes enhanced cell migration without changes in cell adhesion

Overexpression of S100P promotes breast cancer metastasis in animals and elevated levels in primary breast cancers are associated with poor patient outcomes. S100P can differentially interact with nonmuscle myosin (NM) isoforms (IIA > IIC > IIB) leading to the redistribution of actomyosin fila...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Min, Wang, Guozheng, Barsukov, Igor L., Gross, Stephane R., Smith, Richard, Rudland, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108782/
https://www.ncbi.nlm.nih.gov/pubmed/32065231
http://dx.doi.org/10.1042/BCJ20190644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108782/
https://www.ncbi.nlm.nih.gov/pubmed/32065231
http://dx.doi.org/10.1042/BCJ20190644

Ejemplares similares