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Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38

Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of the most widespread tick-borne viral infection in humans. CCHFV encodes a secreted glycoprotein (GP38) of unknown function that is the target of a protective antibody. Here, we present the crystal structure of GP38 at a resoluti...

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Detalles Bibliográficos
Autores principales: Mishra, Akaash K., Moyer, Crystal L., Abelson, Dafna M., Deer, Daniel J., El Omari, Kamel, Duman, Ramona, Lobel, Leslie, Lutwama, Julius J., Dye, John M., Wagner, Armin, Chandran, Kartik, Cross, Robert W., Geisbert, Thomas W., Zeitlin, Larry, Bornholdt, Zachary A., McLellan, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108853/
https://www.ncbi.nlm.nih.gov/pubmed/31996434
http://dx.doi.org/10.1128/JVI.02005-19