The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition

Pannexins are large-pore forming channels responsible for ATP release under a variety of physiological and pathological conditions. Although predicted to share similar membrane topology with other large-pore forming proteins such as connexins, innexins, and LRRC8, pannexins have minimal sequence sim...

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Detalles Bibliográficos
Autores principales: Michalski, Kevin, Syrjanen, Johanna L, Henze, Erik, Kumpf, Julia, Furukawa, Hiro, Kawate, Toshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108861/
https://www.ncbi.nlm.nih.gov/pubmed/32048993
http://dx.doi.org/10.7554/eLife.54670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108861/
https://www.ncbi.nlm.nih.gov/pubmed/32048993
http://dx.doi.org/10.7554/eLife.54670

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