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The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition
Pannexins are large-pore forming channels responsible for ATP release under a variety of physiological and pathological conditions. Although predicted to share similar membrane topology with other large-pore forming proteins such as connexins, innexins, and LRRC8, pannexins have minimal sequence sim...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108861/ https://www.ncbi.nlm.nih.gov/pubmed/32048993 http://dx.doi.org/10.7554/eLife.54670 |