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Identification of novel regulators of STAT3 activity

STAT3 mediates signalling downstream of cytokine and growth factor receptors where it acts as a transcription factor for its target genes, including oncogenes and cell survival regulating genes. STAT3 has been found to be persistently activated in many types of cancers, primarily through its tyrosin...

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Detalles Bibliográficos
Autores principales: Parri, Elina, Kuusanmäki, Heikki, van Adrichem, Arjan J., Kaustio, Meri, Wennerberg, Krister
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108870/
https://www.ncbi.nlm.nih.gov/pubmed/32231398
http://dx.doi.org/10.1371/journal.pone.0230819