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Hypoxia-induced up-regulation of miR-27a promotes paclitaxel resistance in ovarian cancer

Ovarian cancer (OC) is a malignant tumor with high mortality in women. Although cancer patients initially respond to paclitaxel chemotherapy following surgery, most patients will relapse after 12–24 months and gradually die from chemotherapy resistance. In OC, cancer cells become resistant to paclit...

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Detalles Bibliográficos
Autores principales: Feng, Lanlan, Shen, Fangrong, Zhou, Jinhua, Li, Yan, Jiang, Rong, Chen, Youguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109003/
https://www.ncbi.nlm.nih.gov/pubmed/32190895
http://dx.doi.org/10.1042/BSR20192457