Podocyte-targeted Heme Oxygenase (HO)-1 overexpression exacerbates age-related pathology in the rat kidney

Although Heme Oxygenase-1 (HO-1) induction in various forms of kidney injury is protective, its role in age-related renal pathology is unknown. In the ageing kidney there is nephron loss and lesions of focal glomerulosclerosis, interstitial fibrosis, tubular atrophy and arteriolosclerosis. Underlyin...

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Detalles Bibliográficos
Autores principales: Poulaki, Elpida, Detsika, Maria G., Fourtziala, Eythimia, Lianos, Elias A., Gakiopoulou, Hariklia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109035/
https://www.ncbi.nlm.nih.gov/pubmed/32235880
http://dx.doi.org/10.1038/s41598-020-62016-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109035/
https://www.ncbi.nlm.nih.gov/pubmed/32235880
http://dx.doi.org/10.1038/s41598-020-62016-9

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