Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway

Potassium depletion affects AQP2 expression and the cellular composition of the kidney collecting duct. This, in turn, contributes to the development of a secondary form of nephrogenic diabetes insipidus and hypokalemic nephropathy. Here we show that after 14 days of potassium depletion, the cellula...

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Detalles Bibliográficos
Autores principales: Iervolino, Anna, Prosperi, Federica, De La Motte, Luigi R., Petrillo, Federica, Spagnuolo, Manuela, D’Acierno, Mariavittoria, Siccardi, Sabrina, Perna, Alessandra F., Christensen, Birgitte M., Frische, Sebastian, Capasso, Giovambattista, Trepiccione, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109050/
https://www.ncbi.nlm.nih.gov/pubmed/32235870
http://dx.doi.org/10.1038/s41598-020-61882-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109050/
https://www.ncbi.nlm.nih.gov/pubmed/32235870
http://dx.doi.org/10.1038/s41598-020-61882-7

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