Cargando…

Potassium depletion induces cellular conversion in the outer medullary collecting duct altering Notch signaling pathway

Potassium depletion affects AQP2 expression and the cellular composition of the kidney collecting duct. This, in turn, contributes to the development of a secondary form of nephrogenic diabetes insipidus and hypokalemic nephropathy. Here we show that after 14 days of potassium depletion, the cellula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iervolino, Anna, Prosperi, Federica, De La Motte, Luigi R., Petrillo, Federica, Spagnuolo, Manuela, D’Acierno, Mariavittoria, Siccardi, Sabrina, Perna, Alessandra F., Christensen, Birgitte M., Frische, Sebastian, Capasso, Giovambattista, Trepiccione, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109050/ https://www.ncbi.nlm.nih.gov/pubmed/32235870 http://dx.doi.org/10.1038/s41598-020-61882-7

Ejemplares similares

Corrigendum: Integrin Beta 1 Is Crucial for Urinary Concentrating Ability and Renal Medulla Architecture in Adult Mice
por: Iervolino, Anna, et al.
Publicado: (2018)

Integrin Beta 1 Is Crucial for Urinary Concentrating Ability and Renal Medulla Architecture in Adult Mice
por: Iervolino, Anna, et al.
Publicado: (2018)

Bardet–Biedl syndrome: The pleiotropic role of the chaperonin‐like BBS6, 10, and 12 proteins
por: Gupta, Neha, et al.
Publicado: (2022)

ERK1,2 Signalling Pathway along the Nephron and Its Role in Acid-base and Electrolytes Balance
por: Capolongo, Giovanna, et al.
Publicado: (2019)

Selective Dicer Suppression in the Kidney Alters GSK3β/β-Catenin Pathways Promoting a Glomerulocystic Disease
por: Iervolino, Anna, et al.
Publicado: (2015)

Single nephron glomerular filtration rate measured by linescan multiphoton microscopy compared to conventional micropuncture
por: Costanzo, Vincenzo, et al.
Publicado: (2022)

Characterization of five novel vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus reveals a role of tolvaptan for M272R-V2R mutation
por: Prosperi, Federica, et al.
Publicado: (2020)

Lipopolysaccharide directly inhibits bicarbonate absorption by the renal outer medullary collecting duct
por: Tsuruoka, Shuichi, et al.
Publicado: (2020)

The SGLT2-inhibitor dapagliflozin improves neutropenia and neutrophil dysfunction in a mouse model of the inherited metabolic disorder GSDIb
por: Resaz, Roberta, et al.
Publicado: (2021)

Atorvastatin does not ameliorate nephrogenic diabetes insipidus induced by lithium or potassium depletion in mice
por: Thomsen, Maria L., et al.
Publicado: (2021)

The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo
por: Engbjerg, Jacob Schade, et al.
Publicado: (2022)

Kidney and blood pressure regulation—latest evidence for molecular mechanisms
por: Suzumoto, Yoko, et al.
Publicado: (2023)

A scale space approach for unsupervised feature selection in mass spectra classification for ovarian cancer detection
por: Ceccarelli, Michele, et al.
Publicado: (2009)

GALT Protein Database, a Bioinformatics Resource for the Management and Analysis of Structural Features of a Galactosemia-related Protein and Its Mutants
por: d’Acierno, Antonio, et al.
Publicado: (2009)

Comparison of Isotonic Activation of Cell Volume Regulation in Rat Peritoneal Mesothelial Cells and in Kidney Outer Medullary Collecting Duct Principal Cells
por: Baturina, Galina S., et al.
Publicado: (2021)

An extensible six-step methodology to automatically generate fuzzy DSSs for diagnostic applications
por: d'Acierno, Antonio, et al.
Publicado: (2013)

Regulation of urinary calcium excretion by vasopressin
por: Anastasio, Pietro, et al.
Publicado: (2020)

Pretargeted immunoscintigraphy in patients with medullary thyroid carcinoma.
por: Magnani, P., et al.
Publicado: (1996)

Artificial Neural Networks for Forecasting Passenger Flows on Metro Lines
por: Gallo, Mariano, et al.
Publicado: (2019)

The Angiotensin II Type 1 Receptor-Associated Protein Attenuates Angiotensin II-Mediated Inhibition of the Renal Outer Medullary Potassium Channel in Collecting Duct Cells
por: Polidoro, Juliano Zequini, et al.
Publicado: (2021)

Effects of cadmium chloride on mouse inner medullary collecting duct cells
por: Park, Eun-Kee, et al.
Publicado: (2013)

Roflumilast and aquaporin‐2 regulation in rat renal inner medullary collecting duct
por: Umejiego, Ezigbobiara N., et al.
Publicado: (2017)

Adrenomedullin Inhibits Osmotic Water Permeability in Rat Inner Medullary Collecting Ducts
por: Ma, Fuying, et al.
Publicado: (2020)

Phosphatases Decrease Water and Urea Permeability in Rat Inner Medullary Collecting Ducts
por: Wang, Yanhua, et al.
Publicado: (2023)

Fluid shear stress triggers cholesterol biosynthesis and uptake in inner medullary collecting duct cells, independently of nephrocystin-1 and nephrocystin-4
por: Garfa Traoré, Meriem, et al.
Publicado: (2023)

Qualitative Aspects of Some Traditional Landraces of the Tomato “Piennolo” (Solanum lycopersicum L.) of the Campania Region, Southern Italy
por: Fratianni, Florinda, et al.
Publicado: (2020)

Exploring Key Challenges of Understanding the Pathogenesis of Kidney Disease in Bardet–Biedl Syndrome
por: Marchese, Emanuela, et al.
Publicado: (2020)

Notch Signaling Regulates Bile Duct Morphogenesis in Mice
por: Lozier, Julie, et al.
Publicado: (2008)

Huge thyroglossal duct cyst at the supra-sternal notch
por: Abebe, Engida, et al.
Publicado: (2019)

Biochemical Characterization of Traditional Varieties of Apricots (Prunus armeniaca L.) of the Campania Region, Southern Italy
por: Fratianni, Florinda, et al.
Publicado: (2021)

Potential therapeutic benefits of unconventional oils: assessment of the potential in vitro biological properties of some Rubiaceae, Cucurbitaceae, and Brassicaceae seed oils
por: Fratianni, Florinda, et al.
Publicado: (2023)

Aldosterone does not alter endothelin B receptor signaling in the inner medullary collecting duct
por: Ramkumar, Nirupama, et al.
Publicado: (2017)

Aldosterone Decreases Vasopressin-Stimulated Water Reabsorption in Rat Inner Medullary Collecting Ducts
por: Wang, Yanhua, et al.
Publicado: (2020)

Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models
por: Siegerist, Florian, et al.
Publicado: (2021)

The developmental origins of Notch-driven intrahepatic bile duct disorders
por: Martinez Lyons, Anabel, et al.
Publicado: (2021)

NOTCH signalling – a core regulator of bile duct disease?
por: Martinez Lyons, Anabel, et al.
Publicado: (2023)

Claudin-19 Is Regulated by Extracellular Osmolality in Rat Kidney Inner Medullary Collecting Duct Cells
por: Ziemens, Annalisa, et al.
Publicado: (2019)

Tumor Suppressor Role of Notch1 and Raf-1 Signaling in Medullary Thyroid Cancer Cells
por: Kunnimalaiyaan, Muthusamy, et al.
Publicado: (2007)

Nephroplex: a kidney-focused NGS panel highlights the challenges of PKD1 sequencing and identifies a founder BBS4 mutation
por: Zacchia, Miriam, et al.
Publicado: (2021)

Urine concentrating defect as presenting sign of progressive renal failure in Bardet–Biedl syndrome patients
por: Zacchia, Miriam, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_k5ejdga3jke1qo0bsikjgnc2it