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The life cycle of cancer-associated fibroblasts within the tumour stroma and its importance in disease outcome

The tumour microenvironment (TME) determines vital aspects of tumour development, such as tumour growth, metastases and response to therapy. Cancer-associated fibroblasts (CAFs) are abundant and extremely influential in this process and interact with cellular and matrix TME constituents such as endo...

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Detalles Bibliográficos
Autores principales: D’Arcangelo, Elisa, Wu, Nila C., Cadavid, Jose L., McGuigan, Alison P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109057/
https://www.ncbi.nlm.nih.gov/pubmed/31992854
http://dx.doi.org/10.1038/s41416-019-0705-1