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The life cycle of cancer-associated fibroblasts within the tumour stroma and its importance in disease outcome
The tumour microenvironment (TME) determines vital aspects of tumour development, such as tumour growth, metastases and response to therapy. Cancer-associated fibroblasts (CAFs) are abundant and extremely influential in this process and interact with cellular and matrix TME constituents such as endo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109057/ https://www.ncbi.nlm.nih.gov/pubmed/31992854 http://dx.doi.org/10.1038/s41416-019-0705-1 |