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Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin

The interplay between keratinocytes and immune cells, especially T cells, plays an important role in the pathogenesis of chronic inflammatory skin diseases. During psoriasis, keratinocytes attract T cells by releasing chemokines, while skin-infiltrating self-reactive T cells secrete proinflammatory...

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Detalles Bibliográficos
Autores principales: Orlik, Christian, Deibel, Daniel, Küblbeck, Johanna, Balta, Emre, Ganskih, Sabina, Habicht, Jüri, Niesler, Beate, Schröder-Braunstein, Jutta, Schäkel, Knut, Wabnitz, Guido, Samstag, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109061/
https://www.ncbi.nlm.nih.gov/pubmed/31324882
http://dx.doi.org/10.1038/s41423-019-0261-x