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Modification of Adenovirus vaccine vector-induced immune responses by expression of a signalling molecule

Adenoviral vectors are being developed as vaccines against infectious agents and tumour-associated antigens, because of their ability to induce cellular immunity. However, the protection afforded in animal models has not easily translated into primates and clinical trials, underlying the need for im...

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Detalles Bibliográficos
Autores principales: Rollier, Christine S., Spencer, Alexandra J., Sogaard, Karen Colbjorn, Honeycutt, Jared, Furze, Julie, Bregu, Migena, Gilbert, Sarah C., Wyllie, David, Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109070/
https://www.ncbi.nlm.nih.gov/pubmed/32235848
http://dx.doi.org/10.1038/s41598-020-61730-8