Elevated intracellular copper contributes a unique role to kidney fibrosis by lysyl oxidase mediated matrix crosslinking

Copper ions play various roles in mammalian cells, presumably due to their involvement in different enzymatic reactions. Some studies indicated that serum copper correlates with fibrosis in organs, such as liver and lung. However, the mechanism is unknown. Here, we explored the role of copper in kid...

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Detalles Bibliográficos
Autores principales: Niu, Yang-yang, Zhang, Ying-ying, Zhu, Zhi, Zhang, Xiao-qin, Liu, Xi, Zhu, Sai-ya, Song, Ye, Jin, Xian, Lindholm, Bengt, Yu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109154/
https://www.ncbi.nlm.nih.gov/pubmed/32235836
http://dx.doi.org/10.1038/s41419-020-2404-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109154/
https://www.ncbi.nlm.nih.gov/pubmed/32235836
http://dx.doi.org/10.1038/s41419-020-2404-5

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