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Distinct effects of etoposide on glutamine-addicted neuroblastoma

The majority of anticancer drugs are DNA-damaging agents, and whether or not they may directly target mitochondria remains unclear. In addition, tumors such as neuroblastoma exhibit addiction to glutamine in spite of it being a nonessential amino acid. Our aim was to evaluate the direct effect of wi...

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Detalles Bibliográficos
Autores principales: Valter, Kadri, Maximchik, Polina, Abdrakhmanov, Alibek, Senichkin, Viacheslav, Zhivotovsky, Boris, Gogvadze, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109159/
https://www.ncbi.nlm.nih.gov/pubmed/31392350
http://dx.doi.org/10.1007/s00018-019-03232-z