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Low sun exposure increases multiple sclerosis risk both directly and indirectly

OBJECTIVE: We aimed to study (1) to what extent the influence of low sun exposure on multiple sclerosis (MS) risk is mediated by low vitamin D levels; (2) whether low sun exposure or vitamin D deficiency act synergistically with HLA-DRB1*15:01 and absence of HLA-A*02:01. METHODS: We used two populat...

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Detalles Bibliográficos
Autores principales: Hedström, Anna Karin, Olsson, Tomas, Kockum, Ingrid, Hillert, Jan, Alfredsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109160/
https://www.ncbi.nlm.nih.gov/pubmed/31844981
http://dx.doi.org/10.1007/s00415-019-09677-3