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Clinical Pharmacokinetics and Impact of Hematocrit on Monitoring and Dosing of Tacrolimus Early After Heart and Lung Transplantation

The calcineurin inhibitor tacrolimus is an effective immunosuppressant and is extensively used in solid organ transplantation. In the first week after heart and lung transplantation, tacrolimus dosing is difficult due to considerable physiological changes because of clinical instability, and toxicit...

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Detalles Bibliográficos
Autores principales: Sikma, Maaike A., Hunault, Claudine C., Huitema, Alwin D. R., De Lange, Dylan W., Van Maarseveen, Erik M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109168/
https://www.ncbi.nlm.nih.gov/pubmed/31820394
http://dx.doi.org/10.1007/s40262-019-00846-1