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Data-Driven Modeling of the Bicalutamide Dissolution from Powder Systems

Low solubility of active pharmaceutical compounds (APIs) remains an important challenge in dosage form development process. In the manuscript, empirical models were developed and analyzed in order to predict dissolution of bicalutamide (BCL) from solid dispersion with various carriers. BCL was chose...

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Detalles Bibliográficos
Autores principales: Mendyk, Aleksander, Pacławski, Adam, Szafraniec-Szczęsny, Joanna, Antosik, Agata, Jamróz, Witold, Paluch, Marian, Jachowicz, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109170/
https://www.ncbi.nlm.nih.gov/pubmed/32236750
http://dx.doi.org/10.1208/s12249-020-01660-w