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Thin filament dysfunctions caused by mutations in tropomyosin Tpm3.12 and Tpm1.1
Tropomyosin is the major regulator of the thin filament. In striated muscle its function is to bind troponin complex and control the access of myosin heads to actin in a Ca(2+)-dependent manner. It also participates in the maintenance of thin filament length by regulation of tropomodulin and leiomod...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109180/ https://www.ncbi.nlm.nih.gov/pubmed/31270709 http://dx.doi.org/10.1007/s10974-019-09532-y |