Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration

Metabolic reprogramming of tumor cells involves upregulation of fatty acid (FA) synthesis to support high bioenergetic demands and membrane synthesis. This has been shown for cytosolic synthesis of FAs with up to 16 carbon atoms. Synthesis of long-chain fatty acids (LCFAs), including ω-6 and ω-3 pol...

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Detalles Bibliográficos
Autores principales: Tsachaki, Maria, Strauss, Pirmin, Dunkel, Anja, Navrátilová, Hana, Mladenovic, Natasa, Odermatt, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109200/
https://www.ncbi.nlm.nih.gov/pubmed/31302749
http://dx.doi.org/10.1007/s00018-019-03227-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109200/
https://www.ncbi.nlm.nih.gov/pubmed/31302749
http://dx.doi.org/10.1007/s00018-019-03227-w

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