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Molecular Trajectory of BRCA1 and BRCA2 Mutations

Every cancer carries genomic mutations. Although almost all these mutations arise after fertilization, a minimal count of cancer predisposition mutations are already present at the time of genesis of germ cells. Of the cancer predisposition genes identified to date, BRCA1 and BRCA2 have been determi...

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Detalles Bibliográficos
Autores principales: Hatano, Yuichiro, Tamada, Maho, Matsuo, Mikiko, Hara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109296/
https://www.ncbi.nlm.nih.gov/pubmed/32269964
http://dx.doi.org/10.3389/fonc.2020.00361