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Understanding the role of antibody glycosylation through the lens of severe viral and bacterial diseases

Abundant evidence points to a critical role for antibodies in protection and pathology across infectious diseases. While the antibody variable domain facilitates antibody binding and the blockade of infection, the constant domain (Fc) mediates cross talk with the innate immune system. The biological...

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Detalles Bibliográficos
Autores principales: Irvine, Edward B, Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109349/
https://www.ncbi.nlm.nih.gov/pubmed/32103252
http://dx.doi.org/10.1093/glycob/cwaa018