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Understanding the role of antibody glycosylation through the lens of severe viral and bacterial diseases
Abundant evidence points to a critical role for antibodies in protection and pathology across infectious diseases. While the antibody variable domain facilitates antibody binding and the blockade of infection, the constant domain (Fc) mediates cross talk with the innate immune system. The biological...
Autores principales: | Irvine, Edward B, Alter, Galit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109349/ https://www.ncbi.nlm.nih.gov/pubmed/32103252 http://dx.doi.org/10.1093/glycob/cwaa018 |
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