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MASQC: Next Generation Sequencing Assists Third Generation Sequencing for Quality Control in N6-Methyladenine DNA Identification

DNA N6-methyladenine (6mA) modification has been discovered as the most prevalent DNA modification in prokaryotes and eukaryotes, involving gene expression, DNA replication and repair, and host-pathogen interactions. Single-molecule real-time sequencing (SMRT-seq) can detect 6mA events in prokaryoti...

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Detalles Bibliográficos
Autores principales: Yang, Siqian, Wang, Yaoxin, Chen, Ying, Dai, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109398/
https://www.ncbi.nlm.nih.gov/pubmed/32269589
http://dx.doi.org/10.3389/fgene.2020.00269