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CaSR Induces Osteoclast Differentiation and Promotes Bone Metastasis in Lung Adenocarcinoma

Objective: Explore the mechanism of CaSR's involvement in bone metastasis in lung adenocarcinoma. Methods: Immunohistochemistry (IHC) was used to detect the expression of calcium-sensing receptor (CaSR) in 120 cases of lung adenocarcinoma with bone metastasis. Stably transfected cell lines with...

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Detalles Bibliográficos
Autores principales: Liu, Lian, Fan, Yichang, Chen, Zhaoxin, Zhang, Yujian, Yu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109411/
https://www.ncbi.nlm.nih.gov/pubmed/32269963
http://dx.doi.org/10.3389/fonc.2020.00305