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Neuroprotection against Amyloid-β-Induced DNA Double-Strand Breaks Is Mediated by Multiple Retinoic Acid-Dependent Pathways
In this study, we have investigated the role of all-trans-retinoic acid (RA) as a neuroprotective agent against Aβ(1-42)-induced DNA double-strand breaks (DSBs) in neuronal SH-SY5Y and astrocytic DI TNC(1) cell lines and in murine brain tissues, by single-cell gel electrophoresis. We showed that RA...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109576/ https://www.ncbi.nlm.nih.gov/pubmed/32256561 http://dx.doi.org/10.1155/2020/9369815 |