Cargando…

The RNF20/40 complex regulates p53-dependent gene transcription and mRNA splicing

p53 is a key transcription factor to regulate gene transcription. However, the molecular mechanism of chromatin-associated p53 on gene transcription remains elusive. Here, using unbiased protein affinity purification, we found that the RNF20/40 complex associated with p53 on the chromatin. Further a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Chen, Cui, Yaqi, Liu, Xiuhua, Zhang, Feng, Lu, Lin-Yu, Yu, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109600/
https://www.ncbi.nlm.nih.gov/pubmed/31152661
http://dx.doi.org/10.1093/jmcb/mjz045