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The RNF20/40 complex regulates p53-dependent gene transcription and mRNA splicing
p53 is a key transcription factor to regulate gene transcription. However, the molecular mechanism of chromatin-associated p53 on gene transcription remains elusive. Here, using unbiased protein affinity purification, we found that the RNF20/40 complex associated with p53 on the chromatin. Further a...
Autores principales: | Wu, Chen, Cui, Yaqi, Liu, Xiuhua, Zhang, Feng, Lu, Lin-Yu, Yu, Xiaochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109600/ https://www.ncbi.nlm.nih.gov/pubmed/31152661 http://dx.doi.org/10.1093/jmcb/mjz045 |
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