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Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin

Histone methylation is a context-dependent modification that regulates gene expression, and the trimethylation of histone H3 lysine 27 (H3K27me3) usually induces gene silencing. Overcoming colorectal cancer (CRC) chemoresistance is currently a huge challenge, but the relationship between H3K27me3 mo...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Chen, Xi, Jiang, Yuhang, Liu, Sanhong, Liu, Hanshao, Sun, Xiaohua, Zhang, Haohao, Liu, Zhi, Tao, Yu, Li, Cuifeng, Hu, Yiming, Liu, Dandan, Ye, Deji, Liu, Yongzhong, Wang, Mingliang, Zhang, Xiaoren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109602/
https://www.ncbi.nlm.nih.gov/pubmed/31065671
http://dx.doi.org/10.1093/jmcb/mjz032