VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation

The transforming growth factor-β (TGF-β) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-β family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-β/Smad...

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Detalles Bibliográficos
Autores principales: Li, Yihao, Cui, Chao, Xie, Feng, Kiełbasa, Szymon, Mei, Hailiang, van Dinther, Maarten, van Dam, Hans, Bauer, Andreas, Zhang, Long, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109606/
https://www.ncbi.nlm.nih.gov/pubmed/31291647
http://dx.doi.org/10.1093/jmcb/mjz057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109606/
https://www.ncbi.nlm.nih.gov/pubmed/31291647
http://dx.doi.org/10.1093/jmcb/mjz057

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