Cargando…

VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation

The transforming growth factor-β (TGF-β) family controls embryogenesis, stem cell differentiation, and tissue homeostasis. However, how post-translation modifications contribute to fine-tuning of TGF-β family signaling responses is not well understood. Inhibitory (I)-Smads can antagonize TGF-β/Smad...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yihao, Cui, Chao, Xie, Feng, Kiełbasa, Szymon, Mei, Hailiang, van Dinther, Maarten, van Dam, Hans, Bauer, Andreas, Zhang, Long, ten Dijke, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109606/ https://www.ncbi.nlm.nih.gov/pubmed/31291647 http://dx.doi.org/10.1093/jmcb/mjz057

Ejemplares similares

Involvement of Lgl and Mahjong/VprBP in Cell Competition
por: Tamori, Yoichiro, et al.
Publicado: (2010)

Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4(+) T cells
por: Park, Jung-Eun, et al.
Publicado: (2023)

VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation
por: Ghate, Nikhil Baban, et al.
Publicado: (2023)

miRNA-1236 Inhibits HIV-1 Infection of Monocytes by Repressing Translation of Cellular Factor VprBP
por: Ma, Li, et al.
Publicado: (2014)

VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer
por: Ghate, Nikhil Baban, et al.
Publicado: (2021)

Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer
por: Ghate, Nikhil B., et al.
Publicado: (2023)

VprBP/DCAF1 triggers melanomagenic gene silencing through histone H2A phosphorylation
por: Shin, Yonghwan, et al.
Publicado: (2023)

VprBP/DCAF1 Triggers Melanomagenic Gene Silencing through Histone H2A Phosphorylation
por: Shin, Yonghwan, et al.
Publicado: (2023)

HIV-1 Vpr Induces the Degradation of ZIP and sZIP, Adaptors of the NuRD Chromatin Remodeling Complex, by Hijacking DCAF1/VprBP
por: Maudet, Claire, et al.
Publicado: (2013)

DCAF1 (VprBP): emerging physiological roles for a unique dual-service E3 ubiquitin ligase substrate receptor
por: Schabla, N Max, et al.
Publicado: (2018)

Lentiviral Vpx Accessory Factor Targets VprBP/DCAF1 Substrate Adaptor for Cullin 4 E3 Ubiquitin Ligase to Enable Macrophage Infection
por: Srivastava, Smita, et al.
Publicado: (2008)

Tumor suppressor protein Lgl mediates G1 cell cycle arrest at high cell density by forming an Lgl-VprBP-DDB1 complex
por: Yamashita, Kazunari, et al.
Publicado: (2015)

VprBP (DCAF1): a promiscuous substrate recognition subunit that incorporates into both RING-family CRL4 and HECT-family EDD/UBR5 E3 ubiquitin ligases
por: Nakagawa, Tadashi, et al.
Publicado: (2013)

Opposing USP19 splice variants in TGF-β signaling and TGF-β-induced epithelial–mesenchymal transition of breast cancer cells
por: Zhang, Jing, et al.
Publicado: (2023)

HIV-1 Vpr-Mediated G2 Arrest Involves the DDB1-CUL4A(VPRBP) E3 Ubiquitin Ligase
por: Belzile, Jean-Philippe, et al.
Publicado: (2007)

Formation of Mobile Chromatin-Associated Nuclear Foci Containing HIV-1 Vpr and VPRBP Is Critical for the Induction of G2 Cell Cycle Arrest
por: Belzile, Jean-Philippe, et al.
Publicado: (2010)

TGF-β-Induced Endothelial to Mesenchymal Transition Is Determined by a Balance Between SNAIL and ID Factors
por: Ma, Jin, et al.
Publicado: (2021)

New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration
por: Pasteuning-Vuhman, Svitlana, et al.
Publicado: (2017)

The Post-translational Modifications of Smurf2 in TGF-β Signaling
por: Bai, Yangjinming, et al.
Publicado: (2020)

Effects of Activin and TGFβ on p21 in Colon Cancer
por: Bauer, Jessica, et al.
Publicado: (2012)

Regulation of endothelial cell plasticity by TGF-β
por: van Meeteren, Laurens A., et al.
Publicado: (2011)

Defining the Interactions and Role of DCAF1/VPRBP in the DDB1-Cullin4A E3 Ubiquitin Ligase Complex Engaged by HIV-1 Vpr to Induce a G(2) Cell Cycle Arrest
por: Gérard, Francine C. A., et al.
Publicado: (2014)

An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma
por: Morabito, Morgane, et al.
Publicado: (2019)

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells
por: Marvin, Dieuwke L., et al.
Publicado: (2022)

Ultraconserved elements (UCEs) resolve the phylogeny of Australasian smurf-weevils
por: Van Dam, Matthew H., et al.
Publicado: (2017)

TGFβ Signaling and Cardiovascular Diseases
por: Pardali, Evangelia, et al.
Publicado: (2012)

TGF-β in progression of liver disease
por: Dooley, Steven, et al.
Publicado: (2011)

Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer
por: Bauer, Jessica, et al.
Publicado: (2015)

An anti-cancer Smurf
por: Zhao, Keji, et al.
Publicado: (2012)

Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition
por: Boschert, Verena, et al.
Publicado: (2013)

Correction: Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition
por: Boschert, Verena, et al.
Publicado: (2014)

Activin E is a TGFβ ligand that signals specifically through activin receptor-like kinase 7
por: Vestal, Kylie A, et al.
Publicado: (2023)

Vpr makes holes
por: Wells, William A.
Publicado: (2001)

Vpr Is a VIP: HIV Vpr and Infected Macrophages Promote Viral Pathogenesis
por: Lubow, Jay, et al.
Publicado: (2020)

Correction: Ultraconserved elements (UCEs) resolve the phylogeny of Australasian smurf-weevils
por: Van Dam, Matthew H., et al.
Publicado: (2018)

Different Immunoregulation Roles of Activin A Compared With TGF-β
por: Li, Fanglin, et al.
Publicado: (2022)

JNK-Dependent cJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses
por: Sundqvist, Anders, et al.
Publicado: (2019)

Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors
por: Olsen, Oddrun Elise, et al.
Publicado: (2020)

TGF-β Signaling in Breast Cancer Cell Invasion and Bone Metastasis
por: Drabsch, Yvette, et al.
Publicado: (2011)

ERK-Smurf1-RhoA signaling is critical for TGFβ-drived EMT and tumor metastasis
por: Zheng, Jianzhong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uc3prel9u46c7263oou16oihgt