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SOX2 in cancer stemness: tumor malignancy and therapeutic potentials

Cancer stem cells (CSCs), a minor subpopulation of tumor bulks with self-renewal and seeding capacity to generate new tumors, posit a significant challenge to develop effective and long-lasting anti-cancer therapies. The emergence of drug resistance appears upon failure of chemo-/radiation therapy t...

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Detalles Bibliográficos
Autores principales: Mamun, Mahfuz Al, Mannoor, Kaiissar, Cao, Jun, Qadri, Firdausi, Song, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109607/
https://www.ncbi.nlm.nih.gov/pubmed/30517668
http://dx.doi.org/10.1093/jmcb/mjy080