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Megakaryocyte volume modulates bone marrow niche properties and cell migration dynamics

All hematopoietic cells that develop in the bone marrow must cross the endothelial barrier to enter the blood circulation. Blood platelets, however, are released by bigger protrusions of huge progenitor cells, named megakaryocytes, and enter the blood stream as so-called proplatelets before fragment...

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Detalles Bibliográficos
Autores principales: Gorelashvili, Maximilian G., Angay, Oğuzhan, Hemmen, Katherina, Klaus, Vanessa, Stegner, David, Heinze, Katrin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109717/
https://www.ncbi.nlm.nih.gov/pubmed/31248970
http://dx.doi.org/10.3324/haematol.2018.202010