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Thrombomodulin-expressing monocytes are associated with low-risk features in myelodysplastic syndromes and dampen excessive immune activation

The bone marrow of patients with low-risk myelodysplastic syndromes (MDS) is often an inflammatory environment and associated with an active cellular immune response. An active immune response generally contributes to antitumor responses and may prevent disease progression. However, chronic immune s...

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Detalles Bibliográficos
Autores principales: van Leeuwen-Kerkhoff, Nathalie, Westers, Theresia M., Poddighe, Pino J., de Gruijl, Tanja D., Kordasti, Shahram, van de Loosdrecht, Arjan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109736/
https://www.ncbi.nlm.nih.gov/pubmed/31273091
http://dx.doi.org/10.3324/haematol.2019.219303